Industrial production of vitamin b12 pdf

Search life-sciences literature Over 39 million articles, preprints and more Search Advanced search. This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy. Abstract Available from publisher site using DOI. A subscription may be required. Search articles by 'Wei Xia'.

Wei Chen Search articles by 'Wei Chen'. Chen W ,. Peng WF ,. Li KT. Affiliations 1 author 1. Share this article Share with email Share with twitter Share with linkedin Share with facebook. Abstract The aerobic Pseudomonas denitrificans is widely used for industrial and commercial vitamin B12 fermentation, due to its higher productivity compared to the anaerobic vitamin Bproducing microorganisms.

This paper aimed to develop a cost-effective fermentation medium for industrial vitamin B12 production by P. It was found that maltose syrup a low-cost syrup from corn starch by means of enzymatic or acid hydrolysis and corn steep liquor CSL, a by-product of starch industry were greatly applicable to vitamin B12 production by P.

Under the optimal fermentation medium performed by response surface methodology, Therefore, maltose syrups and CSL were the efficient and economical substrates for industrial vitamin B12 fermentation by P.

Full text links Read article at publisher's site DOI : References Articles referenced by this article 26 Microbial production of vitamin B Vitamin B unique metalorganic compounds and the most complex vitamins.

Improvement of adenosylcobalamin production by metabolic control strategy in Propionibacterium freudenreichii. Improved large-scale production of vitamin B12 by Pseudomonas denitrificans with betaine feeding. Show 10 more references 10 of Smart citations by scite. The number of the statements may be higher than the number of citations provided by EuropePMC if one paper cites another multiple times or lower if scite has not yet processed some of the citing articles.

Explore citation contexts and check if this article has been supported or disputed. Jump to Page. Search inside document. V Vitamin B12 is known as cobalamin. Energy production Most B12 functions can be performed by folate another B vitamin.

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Pastoral Song James Rebanks. A Wild Idea Jonathan Franklin. Production of vitamin B12 1. Contents Introduction Cobalamin-still a chemical fortification Structure Biosynthesis of cyanocobalamin Sources and Occurrence Deficiency Dietary recommendations for humans Vitamin-B12 derivatives Organisms for the production of Vitamin-B12 Production of cyanocobalamin Uses of cyanocobalamin 3.

Nomenclature and classification Vitamins can be broadly classified into two main categories 1. Biosynthesis of Cobalamin 9. Steps involved in production The medium is incubated at C for 24hrs without aeration. It is incubated for 2days at C without agitation. Stainless steel bioreactor is used. The medium is incubated at C for 24hrs without aeration, pH is adjusted to 6.

Isolation of cyanocobalamin Uses of Vitamin B12 Vitamin B12 or cobalamin has a wide spectrum of benefits to human health. Therefore a wide scope exists for extensive research in recovering vitamins from fermentation broth with minimum number of steps. Thank you. Arya Chinnu Dec. SalmaAlaa18 Dec. Marisa Thomas Dec.